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Beef Tallow in Skincare: What the Science Actually Says

beef-tallow

Beef tallow is having a moment. Once confined to the kitchen, this rendered animal fat has become one of the most talked about skincare ingredients on social media and praised by wellness communities as a “natural” alternative to moisturisers and barrier creams

But does the trend hold up to scrutiny? And more importantly, is it right for your skin?

In this guide, consultant dermatologist and Klira founder Dr. Emma Craythorne cuts through the noise to explain what the science actually says about beef tallow in skincare, from how it interacts with the skin barrier to why not all fatty acids are created equal.

Watch: Dr. Emma Craythorne on Beef Tallow and the Science of Skin 

What Is Beef Tallow and Why Is It Trending?

Beef tallow is a rendered fat derived from cattle, composed largely of saturated and monounsaturated fatty acids. Its resurgence in skincare is driven by the “back to basics” wellness movement, which champions natural, single-ingredient products and positions synthetic skincare as inherently harmful.

Advocates claim tallow is uniquely compatible with human skin because its fatty acid profile broadly resembles the lipids found in the skin. And while there is a kernel of scientific truth in that the type of fatty acids matters the story is more nuanced than the trend suggests. 

How Does Beef Tallow Interact with the Skin?

Beef tallow is rich in the following fatty acids:

  • Oleic acid (Omega-9): a monounsaturated fatty acid that penetrates the skin readily

  • Stearic acid: a saturated fat with occlusive (sealing) properties

  • Palmitic acid: another saturated fatty acid commonly found in skin lipids

One of the reasons tallow has attracted attention is its potential to reduce transepidermal water loss (TEWL), the process by which water evaporates through the outer layers of the skin into the environment. A healthy, intact skin barrier minimises TEWL; a compromised one allows excessive moisture to escape, leading to dryness, sensitivity, and irritation.

Because tallow forms an occlusive layer on the skin’s surface, it can physically slow TEWL in a similar way to other occlusive ingredients like petrolatum or shea butter.

The Problem with Oleic Acid and Why Molecular Structure Matters

Here is where the science becomes critical, and where we see the trend oversimplified.

Oleic acid, one of the dominant fatty acids in beef tallow, is not universally beneficial for the skin. In fact, research suggests that in certain skin types and conditions, oleic acid may actually disrupt the skin barrier rather than support it.

The skin barrier is partly maintained by a precise ratio of fatty acids; most critically a balance between linoleic acid (Omega-6) and oleic acid (Omega-9). Skin that is acne-prone, inflamed, or already compromised often has an excess of oleic acid relative to linoleic acid. Adding more oleic acid through tallow may therefore:

  • Further disrupt barrier integrity in sensitive or reactive skin

  • Contribute to congestion and comedone formation in acne-prone or oily skin types

  • Exacerbate conditions such as eczema or seborrhoeic dermatitis in susceptible individuals

The natural origin of an ingredient does not determine its suitability. What matters is its molecular behaviour once it interacts with your specific skin biology.

Natural Doesn’t Always Mean Better

One of the most persistent myths in skincare is that “natural” equals safe, gentle, and effective. Dr. Craythorne’s approach directly challenges this:

At Klira, we believe skincare should be guided by evidence and not trends.

The skincare industry is rife with ingredients that are natural in origin yet problematic in application; from essential oils that trigger photosensitivity to plant-derived compounds that cause allergic reactions. The inverse is equally true: highly refined, pharmaceutical grade ingredients often outperform their natural counterparts in clinical settings precisely because their molecular properties, concentrations, and delivery mechanisms are controlled.

Beef tallow may work well for some people, particularly those with very dry, non-acne-prone skin who benefit from the occlusive properties. But it is not a universal solution and applying it without understanding your skin type could cause more harm than good.

How to Know If an Ingredient Is Right for Your Skin

The question is rarely “is this ingredient good or bad?” it is “is this ingredient right for my skin?”

That depends on understanding your skin at a cellular level: how your skin produces sebum, how well your barrier functions, how your skin responds to inflammation, and how effectively it manages pigmentation and collagen production.

This is precisely why Klira’s approach is built on the SkinSize™ system, a dermatologically rigorous framework developed by Dr. Craythorne that classifies skin into 12 types based on four key functions: melanin, collagen, barrier, and sebum.

Once your SkinSize™ is identified, your Klira Special is prescribed accordingly. A bespoke, freshly compounded night treatment combining both personalised and prescription ingredients in the precise combination and concentration your skin actually needs.

The Bottom Line on Beef Tallow in Skincare

 

Beef Tallow

Klira Special

Formulation basis

Trend led, anecdotal

Dermatologist led, clinical evidence

Personalisation

None

Bespoke to your SkinSize™ 

Oleic acid risk

Uncontrolled and may disrupt barrier

Managed within precise formulation

TEWL reduction

Occlusive, and surface level only

Barrier repair at a cellular level

Suitable for acne-prone skin

Potentially problematic

Formulated to your specific sebum profile

Ingredient quality

Unregulated

Pharmaceutical grade and formulated in our London lab

Discover Your SkinSize™ and What Your Skin Actually Needs

If you are navigating the noise of skincare trends and want to know what is genuinely right for your skin, start with the science.

Take Klira’s free online SkinSize™ test. 51 dermatologically designed questions that analyse your skin’s collagen, melanin, barrier and sebum function and find out exactly what your skin needs.

Start Your Free SkinSize™ Test →

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Klira x Roksanda: London Fashion Week

This London Fashion Week felt incredibly special. Klira partnered with the brilliant womenswear designer Roksanda, whose vision of sophistication without complication resonates so deeply with me. She kindly sent me the most beautiful turquoise satin dress from her Spring/Summer 2026 collection, which I paired with my Klira Dayscript – the perfect duo. 

Walking into the old American Embassy in Grosvenor Square, I felt confident and completely myself. I didn’t wear any foundation – just my glowy Dayscript, a little mascara, and a touch of lipstick. Effortless, natural, uncomplicated. When the first models stepped onto the runway, their luminous, dewy skin reflected exactly the same spirit: a pared-back look that let individuality shine. 

That has always been central to Roksanda’s work. There was no single muse, no single ideal – just women of different ages and styles, each powerful in their own way. I couldn’t help but see the parallel with Klira: we believe every skin is unique, and that’s why our formulations are personalised. Intelligent simplicity for maximum impact. 

The collection was a celebration of bold colour, sculptural shapes, and joyful energy, marking Roksanda’s 20 years in fashion. It felt like the perfect alignment of two brands united by a shared belief in individuality and in empowering people to feel confident in their own skin. 

We carried that same energy into Monday night, when Klira and Roksanda hosted a celebration at Isabel in Mayfair. With cocktails, music, and a room filled with inspiring people, it was the most wonderful way to close the week. For Klira, it also marked our very first London Fashion Week sponsorship – a milestone I’ll never forget. 

What resonated most was the shared conviction that simplicity drives the greatest impact. At Klira, our focus on skin health through intelligent, streamlined formulas mirrors the sophistication I saw in Roksanda’s designs – a true celebration of refinement without complication. 

 

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The Dayscript: SPF and Primer in a Single Step 

Most people know they should wear SPF every day. But the reality of how it fits into a skincare or makeup routine is rarely straightforward. 

Do you apply it before makeup or after? Can you mix it with moisturiser? How are you meant to reapply throughout the day without smudging everything off? 

With The Dayscript: a single, dermatologically designed formula that replaces multiple steps in your morning routine, including SPF and primer. 

SPF Meets Skincare Meets Primer 

The Dayscript isn’t just a moisturiser with SPF. It’s a fully integrated 7-in-1 formulation that protects, hydrates, strengthens and supports the skin – all while delivering high UVA/UVB coverage and a soft-focus, blurred finish that acts like a primer. 

It combines: 

  1. Advanced UV protection – SPF 50 with encapsulated filters that remain stable for up to 8 hours 
  2. Anti-inflammatory defence – to soothe and calm skin 
  3. Antioxidant security – to neutralise daily oxidative stress 
  4. Collagen support – to maintain structure and firmness 
  5. Cellular health – to improve skin function 
  6. Deep hydration – to lock in moisture 
  7. Barrier repair – to protect and strengthen your skin 

That means no layering of incompatible products, no second-guessing, and no extra steps before makeup. 

The Primer Effect 

The texture of The Dayscript has been carefully engineered to leave a breathable, smoothing finish. It acts as a soft-blurring primer, creating a refined base layer with or without makeup. 

This is made possible by our encapsulated sunscreen technology, which not only enhances absorption and skin feel but eliminates the typical SPF chalkiness or pilling. The finish is sheer, weightless and shine-free, so your makeup goes on evenly and stays in place. 

No Need to Reapply 

One of the most common skincare concerns we hear is how to top up SPF throughout the day. Once your makeup is on, reapplying sunscreen becomes a real challenge meaning that most people just don’t reapply. 

That’s where The Dayscript is different. Thanks to its encapsulated filters, protection is retained for up to 8 hours without needing to reapply (as long as you’re not swimming or excessively sweating). 

So from the morning to evening, you’re still protected. 

One Intelligent Formula 

Most routines involve several steps: moisturiser, serum, SPF, primer. But each additional product introduces complexity – often leading to irritation, pilling or reduced effectiveness from poorly layered ingredients. 

The Dayscript simplifies all of this.
• One product.
• 7 essential functions.
• SPF 50 built in.
• Primer finish for seamless makeup application. 

No compromise on skin health or performance. 

The Dayscript + The Special = 24-Hour Skin Health 

Pair The Dayscript with The Klira Special at night – our personalised prescription formula tailored by your SkinSize™ – for complete skin support around the clock. 

One for daytime protection and defence. One for night time transformation. 

Bespoke dermatological skincare. Your skin health, re-coded. 

 

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Repairing Summer Skin Damage: Melasma, Dryness & Sensitivity 

As summer winds down, many of us notice new or worsened skin concerns — from stubborn patches of melasma to an increase in dryness and sensitivity. Sun exposure, heat, and environmental stressors can compromise the skin barrier, making it the perfect time to focus on both repair and protection. 

Melasma: When Hormones Meet Sunshine 

Melasma often presents as brown or grey patches on the face and can be stubborn once it develops. It is commonly triggered by hormonal changes – such as during pregnancy or with oral contraceptive use – which make melanocytes (pigment-producing cells) more active. Sun exposure worsens the condition, as UV radiation further stimulates melanin production, and a genetic predisposition often plays a role. 

  • Why summer makes it worse: Increased UV exposure drives melanocytes to overproduce melanin, causing existing pigmentation to darken and new patches to appear. 
  • What helps: Daily broad-spectrum SPF 50 is non-negotiable to prevent further darkening. For targeted treatment, dermatologist-led options like the Klira Special can help fade existing pigmentation by combining prescription-strength actives (e.g., azelaic acid, tretinoin, and hydroquinone where appropriate) into a formula tailored to your skin. 

Post-Inflammatory Hyperpigmentation (PIH) 

Not all pigmentation after summer is melasma. PIH happens when the skin responds to inflammation (acne, eczema flares, or even insect bites) by producing extra melanin. This is more common in darker skin tones, where melanocytes are naturally more active. 

  • Why summer makes it worse: Heat, sweat, and UV prolong redness and irritation, which can make marks darker and slower to fade. 
  • What helps: Gentle skincare that calms inflammation and reduces irritation, alongside daily SPF. A Klira Special can be personalised to include anti-inflammatory and pigment-suppressing ingredients for faster improvement. 

Dry & Sensitive Skin After Summer 

Long days outdoors, sunscreen re-application, chlorine, and travel can disrupt the skin barrier. Signs include flaking, redness, tightness, and increased sensitivity. 

  • Why it happens: UV exposure and heat accelerate water loss from the skin, while salt water and chlorine strip away natural oils. 
  • What helps: Switch to a gentle, hydrating cleanser, such as the Cetaphil Gentle Cleanser, layer in a soothing moisturiser, and keep SPF in your routine (yes, even as the days get cooler). 

Barrier Repair & Sensitive Skin Ingredients 

Barrier damage is one of the hidden costs of summer. Once the lipid barrier is weakened, skin becomes more reactive. To restore resilience, look for these dermatologist-approved ingredients (all of which are in the Klira Special): 

  • Ceramides: the actual lipids (fats) that make up ~50% of the skin barrier; applying them directly replenishes what’s been lost, locking in moisture and sealing out irritants. 
  • Hyaluronic Acid: restores hydration levels. 
  • Azelaic Acid: calms inflammation and gently evens pigmentation. 

Building a Post-Summer Routine 

This structure ensures you’re protected during the day and repairing overnight: 

Morning 

  1. Gentle cleanser
  2. Moisturiser (optional)
  3. Broad-spectrum SPF 50
  4. Makeup (optional)

Evening 

  1. Gentle cleanser 
  2. Soothing moisturiser 
  3. Klira Special (for melasma/photo-damage repair) 

Professional Treatments Worth Considering 

Sometimes skincare alone isn’t enough. Under professional guidance, certain treatments can complement your at-home routine: 

  • Chemical peels: help shed pigmented skin cells and refresh dull, uneven tone. 
  • IPL or Q-switched laser: may improve resistant pigmentation, though caution is needed with melasma as lasers can sometimes trigger rebound pigmentation. 
  • Tranexamic acid: can be prescribed topically or orally in select cases; it reduces melanocyte overactivity and helps calm inflammation. 
  • Hydroquinone: the gold standard pigment-suppressing agent, but only for short-term use under medical supervision. 

Always consult a dermatologist before starting in-clinic or prescription treatments to ensure safety and effectiveness. 

Protect + Repair Going Forward 

SPF every day: A lightweight, broad-spectrum sunscreen is the cornerstone of both melasma control and barrier recovery. 

Personalised treatment: A Klira Special provides prescription-strength repair for pigmentation and photo-damage, with dermatologist oversight. 

Hydration support: Look for ceramides, niacinamide, and hyaluronic acid to replenish skin barrier function. 

Final Takeaway 

Your skin has been your shield all summer –now it’s your turn to shield and restore it. The right approach is not choosing between protection and repair, but combining both every day. 

Daily SPF prevents new pigmentation from setting in. 

Tailored repair (like the Klira Special) fades existing marks and restores balance. 

Barrier support with hydrating ingredients builds long-term resilience. 

By starting now, you’re not just treating the after-effects of summer – you’re future-proofing your skin for the months ahead. Healthy, even, and resilient skin is achievable when you protect and repair in tandem. 

Find the perfect formula for your skin using our 51-question skin test analyses, looking at your skin’s collagen, melanin, sebum, and barrier. At the end you’ll know your SkinSize™: your true skin type. Get your SkinSize analysis today.

References 

  1. British Association of Dermatologists. Melasma [Internet]. London: British Association of Dermatologists; 2024 [cited 2025 Aug 21]. Available from: https://www.bad.org.uk/pils/melasma 
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Retinol vs Retinoid: What’s the Difference and Which One Is Right for You?

When it comes to powerhouse skincare ingredients, retinoids sit firmly at the top. But what exactly is the difference between retinol and retinoid? If you’ve ever felt confused reading product labels or wondering which one to use, you’re not alone.

Let’s break it down so you know exactly what your skin needs, and when.

What Are Retinoids?

Retinoids are a group of ingredients made from vitamin A – one of the most well-researched and effective ingredients in dermatology. They help to:

  • Boost collagen
  • Help skin cells renew faster and shed old cells1
  • Clear acne
  • Fade dark marks and uneven skin tone
  • Smooth fine lines

Once applied, retinoids are converted by the skin into retinoic acid – the form your skin can use. Retinoic acid enters skin cells and affects how they behave, encouraging them to renew, repair, and function more like healthy, younger skin.

What Is Retinol and How Does It Work?

Retinol is a type of retinoid, but it’s a gentler, over-the-counter version that needs to be converted within your skin into retinoic acid before it starts working. The fewer conversion steps a retinoid needs, the stronger – and sometimes more irritating – it can be. 

Here’s how the most common types compare:

  1. Retinol: moderate strength, needs 2 steps
  2. Retinal: stronger, only 1 step
  3. Tretinoin (topical): prescription-only, active immediately
  4. Isotretinoin (oral): prescription-only, commonly known as Roaccutane, works throughout the body to reduce oil production, unclog pores, and decrease inflammation – making it very effective for severe acne2.

Retinol vs Retinoid: Which One Should You Use?

New to vitamin A? Retinol is a good entry point. It’s effective but gentler – ideal if your skin is sensitive, or you’re just starting your skincare journey.

Need faster, clinical-grade results? Prescription retinoids like tretinoin skip the conversion process altogether. They’re ideal for tackling:

  • Persistent or cystic acne
  • Melasma and stubborn pigmentation
  • Advanced signs of ageing
  • Sun damage

Not sure where to begin? That’s where Klira comes in. Our dermatologist-designed formulas prescribe the exact strength and form of retinoid your skin needs – balanced with the right ingredients to support your barrier and reduce irritation.

Why Does Skin React to Retinoids?

Retinoids change the way your skin behaves – so some initial adjustment is normal. You might experience:

  • Flaking or peeling
  • Dryness
  • Mild redness or tingling
  • Purging (where underlying breakouts surface sooner)

This process isn’t a sign it’s “not working.” In fact, it’s often a sign it is. Your skin is increasing its rate of renewal, which brings some temporary turbulence before balance returns.

Top Tips to Minimise Side Effects

To ensure a smoother journey, follow these retinoid rules:

Start low: When starting Klira, your Klira Special will have a low dose of active ingredients. It is made to be used every night..
Optional Moisturiser: If needed, you can applying moisturiser before or after your Special, waiting 10 minutes between the steps.
Use SPF every morning: Retinoids make your skin more sun-sensitive.
Avoid harsh actives: Skip exfoliants or AHAs/BHAs.
Keep it simple: A basic routine (cleanser + retinoid + moisturiser + SPF) is best when starting out.

If you’re still experiencing discomfort after a few weeks, it’s a sign your formulation may need adjusting—not that retinoids aren’t for you.

What About Pregnancy?

Retinoids – including over-the-counter retinol – are generally not recommended during pregnancy due to the risk of systemic absorption. While the evidence is stronger for oral forms (like isotretinoin), topical forms are best avoided to err on the side of caution. If you’re pregnant or trying to conceive, Klira can recommend alternative actives that support your skin barrier and reduce breakouts without risk.

Common Myths, Busted

“Retinoids thin the skin.”
Quite the opposite – retinoids help build up the dermal layer, improving thickness and elasticity over time.

“More is better.”
Not true. Overusing retinoids or starting too strong can compromise your skin barrier. The key is consistency, not intensity.

“You have to take a break in summer.”
You can use retinoids year-round – just apply at night and never skip SPF.

What Does Klira Recommend?

At Klira, we don’t believe in guesswork or one-size-fits-all skincare. Your skin has unique needs, tolerances, and goals, so we’ve built a system to match.

Our prescription-only Skin Plans are:

  • Clinically tailored based on your SkinSize™, medical information and photographs.
  • Buffered with barrier-supporting ingredients like ceramides, or azelaic acid.
  • Adapted over time as your skin evolves
  • Backed by Consultant Dermatologists

No more wasting money on products that are too weak or too irritating. With Klira, you get the exact formula your skin needs to improve texture, tone, and clarity safely and sustainably.

TL;DR: Retinol vs Retinoid

Too Long Don’t Read!

Retinol Retinoid (e.g. Tretinoin)
Strength Lower Higher
Conversion Required Yes No
Availability OTC Prescription only
Best For Cosmetic use for general skin upkeep Acne, pigmentation, advanced ageing, sun damage
Timeline Slower Faster, more dramatic results
Irritation Risk Lower Higher (unless balanced with the right formula)

Want to Know Which Is Right for You?

Let’s take the guesswork out. With a Klira Special you get:

A personalised prescription
Barrier-boosting support ingredients
Ongoing adjustments from dermatology experts

Start your consultation at Klira

References

  1. Ye S, Lee S, Kang S, Jun SH, Kang NG. Improvement of Skin Condition Through RXR Alpha-Activating Materials. Biomolecules. 2025 Feb 17;15(2):296.

British Association of Dermatologists [Internet]. Bad.org.uk. 2025 [cited 2025 Jul 15]. Available from: https://www.bad.org.uk/pils/isotretinoin/

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Skincare Routine Layering 101: The Correct Order to Apply Products

Understanding the correct order to apply skincare products is essential for maximising their effectiveness and achieving healthy skin. Each product serves a unique purpose and layering them properly ensures optimal absorption and results. In this comprehensive guide, we’ll break down exactly how to layer your skincare products for a simple yet effective routine, focusing particularly on evening (PM) and morning (AM) routines.

Why the Order Matters

The order of your skincare products directly affects their effectiveness. Skincare formulations have different molecular sizes, textures, and active ingredients, all of which determine how well they penetrate the skin. Applying products from the thinnest to the thickest texture ensures that each layer absorbs correctly and works effectively.

Morning Skincare Routine (AM)

Your morning skincare routine should focus on protecting your skin from daily environmental stressors such as UV rays, pollution, and oxidative damage.

Step 1: Cleanser

Morning cleansing refreshes your skin and removes excess oil and any residual skincare products from the night before.

How to Apply:

  1. Apply a gentle cleanser and massage gently into your skin for about 30 seconds.
  2. Rinse thoroughly and pat dry.

Tips:

  • To avoid drying out your skin in the morning, opt for a mild, hydrating cleanser, such as CeraVe Hydrating Cleanser.

Step 2: The Dayscript

Formulated as a 7-in-1 treatment with SPF50 PA++++, The Dayscript replaces multiple morning serums and creams, delivering daily protection, hydration, and skin-strengthening benefits.

How to Apply:

  1. Apply two full finger-lengths of cream to your face each morning after cleansing, massaging gently into the skin. Use the same amount for the neck and décolletage.

    Though the dosage may feel generous, it absorbs quickly – creating The Dayscript’s weightless protective layer.

Evening Skincare Routine (PM)

Evening is the prime time to support your skin’s natural repair and regeneration processes. Here’s how to correctly layer your nighttime skincare products:

Step 1: Cleanser

Cleansing is the foundational step of any skincare routine. It removes makeup, sunscreen, dirt, excess oil, and environmental pollutants from your skin, preparing it for subsequent products.

How to Apply:

  1. Dispense a small amount of cleanser into your hands and gently massage onto your face in circular motions for about 30 seconds.
  2. Rinse thoroughly with lukewarm water.
  3. Pat your face dry gently with a clean towel.

Tips:

  • Use a gentle, sulfate-free cleanser to avoid stripping your skin of its natural oils.
  • If you wear heavy makeup or sunscreen, perform a double cleanse by first using an oil cleanser (e.g. Avène XeraCalm A.D Lipid-Replenishing Cleansing Oil) followed by a gentle water-based cleanser (e.g. Cetaphil Gentle Cleanser).

Step 2: The Klira Special 

Depending on your SkinSize™, your personalised Klira formulation typically contains prescription-strength ingredients like tretinoin, azelaic acid, or peptides, which target specific skin concerns such as acne, hyperpigmentation, or signs of ageing.

How to Apply:

  1. Dispense two pumps of Klira into your hand.
  2. Apply gently to areas of concern or evenly across your face, avoiding the sensitive skin around your eyes and mouth.
  3. Allow the product to fully absorb overnight without rinsing.

Tips:

  • Always follow the directions provided with your Klira Special prescription.
  • Apply 2 pumps of your formula consistently every evening.

Step 3: Moisturiser (Optional)

This an optional step, some users may want to apply an extra layer of moisture if they have dryer skin,  whereas some users can skip this step as their Klira Special will be enough.

How to Apply:

  1. Gently pat it onto your face and neck.

Tips:

  • Choose a moisturiser suited to your skin type, lightweight gels for oily skin and richer creams for dry skin.

General Layering Tips

  • Always move from thinner to thicker consistency products.
  • SPF is ALWAYS the last and most important step.
  • Stay consistent; skincare results improve significantly with regular, sustained use.

Conclusion

Proper skincare layering is key to achieving the best possible results. By following this step-by-step guide, you’ll optimise the benefits of each product, creating a simple yet effective routine tailored to your skin’s needs. Embrace consistency, patience, and gentle care, and you’ll soon see noticeable improvements in your skin’s health and appearance.

References

  1. Bos JD, Meinardi MMHM. The 500 Dalton rule for the skin penetration of chemical compounds and drugs. Experimental Dermatology [Internet]. 2000 Jun [cited 2025 May 30];9(3):165–9. Available from: https://pubmed.ncbi.nlm.nih.gov/10839713/
  2. Elias PM. Optimizing emollient therapy for skin barrier repair in atopic dermatitis. Annals of Allergy Asthma & Immunology [Internet]. 2022 Jan 20 [cited 2025 May 30];128(5):505–11. Available from: https://www.sciencedirect.com/science/article/pii/S1081120622000151
  3. Griffiths TW, Watson RE, Langton AK. Skin ageing and topical rejuvenation strategies. British Journal of Dermatology. 2023;189(Supplement_1):i17–23.

Our Dermatology Team will review your SkinSize™ Analysis, medical information, and photos to decide which ingredients you will receive in your bespoke formula.

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The Right Way to Apply Your Face SPF (and the Common Mistakes to Avoid)

SPF is the single most important product in your skincare routine when it comes to protecting your skin from damage, premature ageing and pigmentation. But are you applying yours properly? Even the best SPF can’t do its job if it’s not used the right way. 

At Klira, we believe your skincare routine should be based on real science – with recommendations that suit your unique SkinSize™. We help you find the right product for your skin needs. But before you even get to product choice, technique matters. Here’s how to apply your face SPF properly to get the full protection promised on the bottle. 

1. You’re Probably Not Using Enough

The biggest mistake? Not applying enough. SPF protection levels (like SPF 30 or SPF 50) are based on lab testing, which assumes the correct amount is used. If you under-apply, you’re not getting the protection stated on the packaging. A general guide is two full finger lengths of product for the face and neck combined.

2. Don’t Rub It Between Your Palms First

It might feel natural to rub SPF between your hands before applying, but this just means half of it ends up absorbed by your palms – not your face. Apply to your hands first and scoop with your fingers.

3. Think Patting, Not Smearing

To get an even film of protection across your face, pat the SPF in gently rather than smearing it around. You’re aiming to create a uniform layer that shields every area of skin.

4. If in Doubt, Go in for a Second Layer

Worried you’ve missed a patch? Simply apply a second layer. SPF works best when applied generously and evenly. It’s better to double up than leave gaps in your protection.

5. Let It Dry Before Makeup

Your SPF doesn’t need to “penetrate” the skin – that’s not how it works. But it does need time to set and form a protective film. This happens very quickly – allow a minute or so before applying makeup.

6. Don’t Miss These Forgotten Areas

Certain areas get overlooked all the time, make sure you cover: 

  • The tops of your ears 
  • The bridge of your nose 
  • The glabella (the area between your eyebrows) 
  • Your neck – SPF should always be taken down to the neck 

These exposed spots are just as vulnerable to sun damage as the rest of your face. 

Discover the Right Skincare for Your Skin 

Knowing how to apply your SPF properly is important, as is choosing the right SPF for your skin. Your SkinSize™ analysis takes the guesswork out of your skincare routine, with expert recommendations based on your skin’s needs. 

Take the SkinSize™ test today to understand your skin on a cellular level. 

Our Dermatology Team will review your SkinSize™ Analysis, medical information, and photos to decide which ingredients you will receive in your bespoke formula.

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Understanding Acne: Causes, Treatments and How to Support Your Skin 

Acne is one of the most common inflammatory skin conditions globally. It affects people of all ethnicities and is most prevalent during adolescence – typically between the ages of 15 and 20. But it’s not just a teenage concern. Acne can start earlier and persist well into adulthood, with an increasing number of adult women experiencing breakouts linked to hormonal sensitivity or subtle endocrine imbalances, even when hormone levels appear normal. 

More Than Skin Deep 

The impact of acne goes beyond the surface. Pimples, blackheads, pustules or scarring can significantly affect confidence, mood and self-esteem – particularly during pivotal life stages or moments of professional development. The psychological effects are often underestimated, but they can be profound. 

What Causes Acne? 

Acne develops in the pilosebaceous unit, which includes the hair follicle and oil gland. Four main processes drive the condition: 

  • Increased sebum (oil) production
  • Blocked pores due to sticky skin cells
  • Overgrowth of Cutibacterium acnes
  • Inflammation

During puberty, rising androgen levels stimulate the oil glands to produce more sebum. If the follicle becomes blocked, this creates the perfect environment for bacteria to thrive triggering inflammation, redness, and swelling. 

The clinical presentation can range from a few blocked pores to widespread, inflamed nodules across the face, back or chest. In darker skin tones, pigmentation changes are common. Even mild acne can leave lasting marks or scars, depending on how the skin heals. 

What Makes Acne Worse? 

Several factors can aggravate acne, including: 

  • Hormonal fluctuations (e.g., during the menstrual cycle) 
  • Comedogenic (pore-clogging) cosmetics 
  • Certain medications like corticosteroids or testosterone-based supplements 
  • Environmental stressors such as heat, humidity and friction 
  • Picking or squeezing spots, which increases the risk of scarring 

The Foundation of Treatment: Topical Retinoids 

For all types of acne, the cornerstone of effective treatment is a topical retinoid. These vitamin A derivatives, such as tretinoin work by: 

  • Unblocking pores 
  • Preventing the build-up of dead skin cells 
  • Reducing early inflammation 
  • Normalising skin cell turnover 

Used consistently over time, a topical retinoid can dramatically improve both non-inflammatory (blackheads) and early inflammatory acne. At Klira, we formulate evidence-based, prescription-strength treatments tailored to your skin’s needs, always starting with this essential foundation. 

When to Add Oral Treatments 

If acne becomes more inflamed – characterised by red bumps or pustules , oral antibiotics may be considered. These help reduce inflammation in the short term but must always be used alongside a topical retinoid to prevent relapse once antibiotics are stopped. 

In females, hormone-sensitive acne is common. Treatments such as the combined oral contraceptive pill or spironolactone can help by reducing the effect of androgens on the skin. These options may be appropriate for persistent breakouts, premenstrual flares, or acne that begins in adulthood. 

When Acne Is Severe 

For severe acne with deep nodules or scarring, oral isotretinoin may be appropriate. This powerful retinoid reduces oil production, inflammation and the formation of new comedones. It’s typically prescribed by a dermatologist and monitored closely due to potential side effects, including skin dryness and the need for contraception.

The Role of Skincare 

Supportive skincare is essential alongside active treatment. Many acne therapies cause dryness or irritation – especially in the first few weeks. A gentle, non-comedogenic moisturiser can: 

  • Soothe irritation 
  • Strengthen the skin barrier 
  • Improve treatment tolerance 

A soap-free cleanser used twice daily helps maintain balance and remove excess oil and debris without stripping the skin. Make-up is fine to use – but removing it thoroughly each evening is key. 

What About Diet? 

There’s growing interest in the link between diet and acne. While the evidence isn’t definitive, high glycaemic foods and dairy (especially skimmed milk) may contribute to breakouts in some individuals. There’s no need for extreme dietary changes – but it’s worth noting personal triggers and maintaining a balanced, nutritious diet. 

Final Thoughts 

Acne is complex and deeply individual, but it’s also highly treatable. At Klira, our prescription-grade treatments are scientifically backed and designed to work with your skin, not against it. Whether you’re navigating adult acne, or hormonal fluctuations, our dermatology-led approach helps you take back control, with real results.

Our Dermatology Team will review your SkinSize™ Analysis, medical information, and photos to decide which ingredients you will receive in your bespoke formula.

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Longevity Tips From a Dermatologist: Healthy Skin & Ageing

Ageing is a privilege, but how you age especially when it comes to your skin is something you can influence. Many people wonder how to maintain healthy, youthful skin for as long as possible. The good news? With the right approach, including SPF, Klira, nutrition, and exercise, you can support your skin’s longevity and overall well-being. 

What is longevity? 

Longevity refers to living a long and healthy life, with a focus on maintaining physical and mental well-being as you age. In skincare, longevity means preserving skin health, strength, and resilience through protective and reparative measures, ensuring that your skin remains vibrant for years to come. 

In this guide, we’ll explore dermatologist-approved longevity tips that go beyond just looking younger – they focus on ageing healthily. From daily sun protection to powerful skincare like Klira, plus diet and lifestyle habits, you’ll learn how to keep your skin strong, resilient, and glowing for years to come. 

What makes our skin age quicker? 

Skin ageing is a natural process, but certain external and lifestyle factors can accelerate it, leading to premature wrinkles, sagging, pigmentation, and loss of elasticity. Understanding these causes allows you to take proactive steps to protect your skin and maintain its health. 

1. Sun exposure & UV damage 

The number one cause of premature skin ageing is exposure to ultraviolet (UV) radiation from the sun. UV damage accounts for up to 80% of visible skin ageing, a process known as photoageing. The two primary types of UV rays that impact the skin are: 

  • UVA: These rays penetrate deep into the skin, breaking down collagen and elastin, leading to fine lines, wrinkles, and sagging. UVA rays can also pass through windows in homes, offices, and cars, meaning unprotected skin is at risk even when indoors or driving. 
  • UVB: These rays mainly affect the skin’s surface, causing sunburn and direct DNA damage, which increases the risk of skin cancer. While UVB is strongest during midday sun exposure, it contributes to cumulative damage over time. Wearing a broad-spectrum SPF 30 or higher every day—even when indoors or on cloudy days is essential to slow skin ageing and prevent damage from UVA and UVB rays. 

2. Smoking 

Smoking is a major contributor to premature ageing. It reduces blood flow to the skin, depletes oxygen and vital nutrients, and triggers the breakdown of collagen and elastin. This results in thinner, more fragile skin, increased wrinkles (especially around the mouth), and a dull, uneven complexion. Smoking also increases oxidative stress, leading to further cellular damage. 

3. Poor diet & nutrient deficiencies 

What you eat directly affects your skin’s ability to repair and maintain itself. Diets high in processed foods, sugar, and unhealthy fats contribute to glycation, a process that stiffens and damages collagen, leading to wrinkles and sagging. On the other hand, a diet rich in antioxidants, healthy fats, and vitamins supports skin repair and longevity.  

4. Lack of exercise 

Regular movement improves circulation, oxygenation, and collagen production, keeping the skin firm and radiant. Exercise also reduces chronic inflammation and oxidative stress, both of which contribute to premature ageing. Sedentary lifestyles, on the other hand, are linked to increased skin dullness, loss of elasticity, and slower cell turnover. 

5. Chronic stress & lack of sleep 

High stress levels and poor sleep habits increase the production of cortisol, a hormone that breaks down collagen and accelerates skin ageing. Chronic stress can also lead to inflammation, dehydration, and a weakened skin barrier, making the skin more prone to fine lines, breakouts, and irritation. Prioritising good sleep, relaxation techniques, and mindfulness can help protect your skin from stress-related ageing. 

Actionable tips for healthy skin ageing 

Now that we’ve covered the main factors that accelerate skin ageing, let’s focus on practical, dermatologist-approved solutions to protect and support your skin’s longevity. By incorporating these steps into your daily routine, you can slow down the ageing process and maintain strong, glowing skin for years to come. 

1. Daily SPF: your first line of defence 

The single most effective way to prevent premature ageing is consistent sun protection. Even on cloudy days or when indoors, your skin is exposed to UVA rays, which penetrate windows and break down collagen. 

  • Best SPF: La Roche-Posay UVmune 400 SPF 50 is one of the most advanced sunscreens available, providing excellent UVA and UVB protection with ultra-long UVA filters. 
  • How to use: Apply a generous amount to your face, neck, ears, and any exposed areas at the end of your morning skincare routine. 
  • Reapplication: Reapply every 2–3 hours if you’re outdoors or sitting near windows. For an easy midday top-up, use a spray or powder SPF over makeup. 

2. Klira: powerful night time skin repair treatment

Klira is a prescription-strength skincare formulation designed to repair and strengthen the skin. Its blend of powerful active ingredients stimulates collagen, reduces pigmentation, improves hydration, and enhances overall skin resilience. 

Key ingredients and benefits: 

  • Azelaic Acid: Helps to reduce inflammation, even out skin tone, and combat oxidative stress. 
  • Cholesterol & hyaluronic acid: Work together to restore skin barrier function and deeply hydrate. 
  • Hydrolysed Collagen: Provides amino acids that support skin repair and elasticity. 
  • How to use: Apply 2 pumps of The Klira Special each night after cleansing.

3. Nutrition: feed your skin from within 

Your diet plays a crucial role in skin repair, hydration, and collagen preservation. A diet rich in antioxidants, healthy fats, and protein supports your skin’s ability to stay firm, plump, and resilient. 

Prioritise: 

  • Vitamin C-rich foods (citrus, berries, peppers) to boost collagen. 
  • Omega-3s (salmon, walnuts, flaxseeds) to maintain hydration and reduce inflammation. 
  • Polyphenols (green tea, dark chocolate, olive oil) to combat oxidative stress. 
  • Collagen-supporting nutrients (bone broth, eggs, soy, leafy greens).
Limit processed foods, sugar, and excessive alcohol, which contribute to glycation (collagen breakdown) and inflammation.

4. Exercise: boost circulation & collagen production 

Movement keeps your skin oxygenated, nourished, and elastic. Exercise increases blood flow, delivers essential nutrients to skin cells, and helps flush out toxins. 

  • Aim for at least 150 minutes of moderate exercise per week (e.g., brisk walking, cycling, pilates). 
  • Strength training supports muscle tone, preventing the loss of facial volume that contributes to sagging. 
  • Yoga and stretching improve circulation and stress management, reducing cortisol (which breaks down collagen). 

5. Quit smoking: reverse & prevent further damage 

If you smoke, quitting is one of the most powerful anti-ageing decisions you can make. The skin begins to recover almost immediately, with improved blood flow and oxygenation leading to better collagen production, reduced fine lines, and a healthier complexion. If quitting is challenging, consider nicotine replacement therapy or professional support. Increasing antioxidant intake can help counteract some of the oxidative damage caused by past smoking. 

6. Prioritising sleep: overnight skin repair 

Skin undergoes its most intensive repair and renewal at night. Poor sleep leads to increased cortisol, which accelerates collagen breakdown, dehydration, and inflammation. 

  • Aim for 7–9 hours of quality sleep per night. 
  • Support overnight skin repair with hydrating skincare (we love La Roche-Posay Lipikar AP+M) and Klira. 
  • Reduce blue light exposure an hour before bed to improve sleep quality. 

Stress management: protect your skin from cortisol damage 

Chronic stress raises cortisol levels, leading to inflammation, breakouts, and premature ageing. Managing stress effectively can preserve collagen and prevent accelerated skin ageing.  

  • Mindfulness & meditation: Even 10 minutes a day can lower cortisol and promote relaxation. 
  • Breathwork & yoga: Help reduce oxidative stress and inflammation. 
  • Outdoor walks & hobbies: Spending time in nature and engaging in enjoyable activities can significantly improve skin and overall health. 

Final thoughts 

Ageing is a privilege, and with the right approach, your skin can remain healthy, resilient, and glowing for years to come. The key to skin longevity isn’t about chasing youth, it’s about protecting, strengthening, and nourishing your skin so it ages well. 

By making daily SPF application non-negotiable, incorporating powerful skincare like Klira, and prioritising a balanced diet, regular exercise, quality sleep, and stress management, you can significantly slow down premature ageing and maintain radiant, strong skin. 

Small, consistent habits make all the difference. Start today, and your future self and skin will thank you.  

Our Dermatology Team will review your SkinSize™ Analysis, medical information, and photos to decide which ingredients you will receive in your bespoke formula.

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Tretinoin UK Guide: Benefits for Acne, Photoaging & Youthful Skin

What is Tretinoin? 

Tretinoin, also known as all-trans retinoic acid, is often hailed as the gold standard in skincare. You’ll be hard-pressed these days to find a dermatologist who doesn’t use Tretinoin on their own skin! It’s a prescription-only derivative of Vitamin A, clinically proven to accelerate skin cell turnover, unclog pores, improve fine lines, and fade pigmentation.

Unlike over-the-counter retinoids like retinol and retinal (retinaldehyde), which require conversion within the skin to become active, Tretinoin works in its active form immediately, delivering faster and more effective results.

Over-the-counter options like retinol must first convert into retinal and then into Tretinoin before becoming active. Retinal is one step closer, making it slightly more effective than retinol, but both are still significantly less potent than prescription Tretinoin.

How Does Tretinoin Work on the Skin?

Boosts Collagen

Tretinoin stimulates the production of collagen, the protein responsible for maintaining skin structure and firmness. It has a few mechanisms through which it does this, but one key way is through its stimulation of fibroblasts, which are the primary cells responsible for producing collagen.

With age, collagen levels naturally decline, leading to wrinkles and sagging skin. Tretinoin helps to restore collagen levels, enhancing skin elasticity and reducing fine lines. This collagen-boosting effect makes it a core ingredient in many anti-ageing regimens.

Speeds Up Cell Turnover

One of Tretinoin’s primary mechanisms is its ability to accelerate cell turnover. This process sheds dead skin cells faster and promotes the growth of fresh, healthy cells. The result? A smoother, more even skin texture and a reduction in fine lines and pigmentation. This increased turnover also prevents pore blockages, reducing breakouts and congestion.

Reduces Acne and Clogged Pores

Initially formulated for acne treatment, Tretinoin is highly effective at keeping pores clear and reducing inflammation. It works by speeding up cell turnover, helping your skin shed dead cells before they have a chance to clog pores. This process not only treats existing breakouts but also helps to prevent new ones from forming, leaving your skin clearer and smoother over time.

Benefits of Tretinoin for Different Skin Concerns

Anti-Ageing and Wrinkle Reduction

Tretinoin remains one of the most effective topical treatments for reducing the appearance of fine lines and wrinkles. Regular use not only smooths existing lines but also prevents new ones from forming by bolstering skin structure. Long-term application improves skin resilience and firmness, delaying visible signs of ageing.

Hyperpigmentation and Skin Texture

By enhancing cell turnover, Tretinoin helps to fade dark spots and even out skin tone. It also smooths rough patches, leading to a glowy complexion which reflects light more evenly. Over time, consistent use diminishes age spots and sun-induced pigmentation, revealing brighter, more even-toned skin.

Acne Management

As a potent retinoid, Tretinoin effectively reduces acne by preventing clogged pores and minimising inflammation. Studies have shown that it decreases the formation of open and closed comedones (blackheads and whiteheads) and reduces inflammatory lesions, making it a preferred choice for dermatologists.

Managing Tretinoin Side Effects

Irritation, Dryness, and Flaking

While highly effective, Tretinoin can cause initial irritation, dryness, and flaking as your skin adjusts. This is a normal part of the process, reflecting its powerful mechanism of action. These effects typically subside with continued use and can be managed with proper hydration and skin barrier-supporting creams.

Safe Use with Moisturisers and SPF

To mitigate irritation, dermatologists recommend pairing Tretinoin with hydrating moisturisers and daily SPF. This helps to protect the skin barrier and minimise sensitivity.

Using broad-spectrum SPF50 sunscreens (or as Dr Emma calls them, ‘radiation filters’) every single day, all year-round, is crucial, as Tretinoin increases photosensitivity. [Although Dr Emma would be the first to tell you that you should be using a radiation filter daily anyway!].

Tretinoin Usage Tips

Starting Slowly

Begin with a low strength and gradually increasing as your skin builds tolerance. This slow introduction helps your skin acclimate, reducing the likelihood of irritation.

Pairing with Barrier-Supporting Ingredients

Supporting Tretinoin with ingredients that fortify the skin barrier can reduce irritation and improve results. Look for hydrating ingredients such as ceramides and hyaluronic acid. 

What to Expect from Pharmacy-Grade Tretinoin

Prescription Tretinoin is available in different formulations, including creams and gels. Strengths typically range from 0.025% to 0.1%, with medical guidance being crucial for achieving optimal results safely. The right formulation often depends on your skin type.

FAQs about Tretinoin

Can I use Tretinoin with other actives?

Yes, but it’s important to be mindful when combining Tretinoin with strong actives like AHAs or BHAs, as this can increase the risk of irritation. Instead, stick to a gentle cleanser, moisturizer, SPF, and a Vitamin C serum for an extra boost.

How long does it take to see results?

A skin cycle – the process where new skin cells move from the bottom layer to the surface – typically takes around 6 weeks. Most Tretinoin users start to see visible improvements within 12 weeks of consistent use (about two skin cycles). After that, the benefits continue to build, and skin health keeps improving over time.

What is Tretinoin used for?

Tretinoin is commonly used to treat acne, reduce signs of aging, fade hyperpigmentation, and improve overall skin texture.

Is long-term use of Tretinoin safe?

Yes, Tretinoin is generally safe for long-term use when monitored by a healthcare provider. However, it’s important to avoid Tretinoin when trying to conceive or during pregnancy. 

Are there side effects from using a Tretinoin prescription?

Some common side effects include dryness, redness, and peeling, especially when you first start using it. These effects usually decrease as your skin adjusts over time.

Tretinoin vs Retinol: What’s the difference?

Tretinoin is a stronger, prescription-only retinoid, while retinol is a milder, over-the-counter option. Tretinoin works faster and more effectively because it doesn’t need to be converted by the skin to become active. In contrast, retinol must first convert into retinal and then into Tretinoin, making it less potent.

References

  1. Kligman AM, Grove GL, Hirose R, Leyden JJ. Topical tretinoin for photoaged skin. J Am Acad Dermatol. 1986;15(4):836–59. Available from: https://doi.org/10.1016/S0190-9622(86)70242-9
  2. Griffiths CE, Russman AN, Majmudar G, Singer RS, Hamilton TA, Voorhees JJ. Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid). N Engl J Med. 1993;329(8):530–5. Available from: https://doi.org/10.1056/NEJM199308193290803
  3. Schmidt N, Gans EH. Tretinoin: a review of its anti-inflammatory properties in the treatment of acne. J Clin Aesthet Dermatol. 2011;4(11):22.
  4. National Institute for Health and Care Excellence (NICE). Acne vulgaris: topical retinoids. Clinical Knowledge Summaries [Internet]. 2023 [cited 2025 May 22]. Available from: https://cks.nice.org.uk/topics/acne-vulgaris/prescribing-information/topical-retinoids/
  5. Tretinoin for acne. Patient.info [Internet]. 2023 [cited 2025 May 22]. Available from: https://patient.info/medicine/tretinoin-for-acne

Our Dermatology Team will review your SkinSize™ Analysis, medical information, and photos to decide which ingredients you will receive in your bespoke formula.