Klira Specials are formulated with a unique base delivery system that eradicates negative side effects normally associated with starting Retinoids.

Klira bases combine ingredients such as ceramides, squalene, glycerine, hydrolysed collagen, aloe and hyaluronic acid that work in synergy to maximise penetration into the skin in the most effective and nourishing way for your SkinSize. Depending on your SkinSize the base will able to deliver the active ingredients in a more precise way. These ingredients are important but the precise ratio in which they are incorporated into the base is more important.

When you bring all this together in one formula, as we have, it delivers maximum clinical results whilst feeling absolutely gorgeous on the skin.

Prescribed dose from 0.01% up to 0.1%

To be very clear, this is the retinoid that has the best evidence behind it. This is the retinoid that is approved by the FDA for treatment of photodamage and acne. No retinol, retinaldehyde or derivative thereof has an approval for these indications. If your SkinSize dictates you could benefit from a retinoid then it is important to use one that will work.

Many people will seek alternatives to tretinoin due to the irritation that can occur. Retinol is a common cosmeceutical found on off-the shelf products that skincare companies know will be easier to use – but that is at the expense of effectiveness. Tretinoin is at least 20 times, and anything up to 100 times more powerful than retinol, The Klira motto is to use the ingredient that works but to ensure it is delivered in the right base for your skin type so that you can get the right benefit with minimal irritation.

Tretinoin is a derivative of Vitamin A, a central and important vitamin for regulation of function within the skin. Tretinoin will change how a cell functions, it speeds up the turnover of older cells and encourages newer skin cells to divide more rapidly and build up the layers of the epidermis, thickening it through cell proliferation at the top level. It also increases the production of hyaluronic acid to keep the skin more plump. It can stimulate collagen production and importantly inhibit the breakdown of collagen. Tretinoin is also important to reduce inflammatory pathways in the skin that can contribute to acne and rosacea.

Prescribed dose from 10% up to 20%

Azelaic acid is an antioxidant that is produced by a yeast that lives on normal human skin. It has number of proven functions to show that is is antibacterial, particularly to reducing the growth of bacteria in the follicle. It stops the blockage and the outlet of the sebaceous glands by regulating growth of the skin cells lining the follicle. It can reduce inflammation and has also been shown to be effective in reducing pigmentation in disorders such as melasma and post inflammatory hyperpigmentation.

Again it is the correct dose that is important and the base in which that dose is delivered. Azelaic Acid has a licence at 15% to be effective in reduction of inflammatory lesions in rosacea and 20% dose for reduction in lesions of acne. At 20 % it has also been shown to be more effective than 2% hydroquinone in treating melasma. Due to the difficulty in formulating.