Ingredients

GREAT SKIN DOESN’T JUST
HAPPEN, IT’S PRESCRIBED

Klira Specials combine the most effective actives with ingredients that work in synergy to deliver cellular change in the most nourishing way for your SkinSize™. Ingredients are important, but the precise ratio in which they are incorporated into the Klira Special is key.

When you bring this together in one formula, the Klira Special delivers maximum clinical results whilst feeling luxurious on the skin.

Discover The Ingredients

The Klira Special offers the most most personalised formula on the market – each one containing up to 11 hand-selected ingredients working in synergy for your SkinSize™. Our pharmaceutical-grade ingredients are kept in strict conditions to ensure peak-potency from the actives. Discover our ingredients and the effect they have on your skin through daily application.

Aloe

This is a skin soother it is rich in phytosterols that calm and hydrate, and reduces transepidermal water loss form the skin. It also allows the transfer of active ingredients in a way that doesn’t cause irritation.

Azelaic Acid

Azelaic acid works by exfoliating the skin, reducing the formation of comedones, as an anti-inflammatory and as an antioxidant. It is a powerhouse of an ingredient that can be used as a reliable treatment for acne, rosacea and pigmentation irregularities. It also works really well with ingredients like Retinoic Acid to help facilitate its absorption.

Capric Trigylceride

These are fatty acids made up from coconut oil or palm kernel oil and then combined with glycerin. Used to formulate and help facilitate delivery of ingredients, but actually with additional benefits in that it really hydrates the skin and is an emollient that works really well but never feels too heavy. It has antioxidant properties to neutralise free radical damage. It is also very low risk for causing skin sensitivity.

Ceramides

Ceramides can be used to rebuild and restore the protective skin barrier. They are particularly important when used in conjunction with other ingredients that form the lipid barrier of the skin. Cholesterol, Ceramides, Free fatty Acids. In the ratio 1:2:1 this mimics the natural skin barrier. These ingredients can be particularly helpful at certain times of life where there are hormonal changes, such as menopause.

Cholesterol

Cholesterol is a molecule added to help support the skins natural barrier function and as an emollient. It is an essential structural component of cell membranes to maintain strength and fluidity. Cholesterol also functions to repair skin that has been stripped of its natural lipids by things like exfoliating or applying an aggressive anti-aging treatment. Due to its ability to strengthen the skin’s barrier, those with sensitive, and dry skin types will likely benefit most from cholesterol-containing creams.

Glycerin

This is one of the most effective hydrators of the skin. It makes the skin feel dewy, and is a wonderful feeling ingredient. It works as a humectant and attracts water in from the environment. As it is fairly small ingredient it can really penetrate to do the job it needs to do. It is really helpful for sensitive skin, and to protect against harsh environments or ingredients.

Ivermectin

This is a really exciting ingredient that has been used in skincare increasingly over the last decade and is becoming the gold standard treatment for a number of conditions. Topical Ivermectin is an effective treatment for inflammatory papulopustular rosacea in adults. It has dual action as an anti-inflammatory and anti-parasitic effect. Positive therapeutic effects of Ivermectin due to its potential anti-inflammatory properties can be achieved in the other facial dermatoses such as perioral dermatitis, seborrheic dermatitis and acne vulgarisms.

Collagen Peptides

Collagen is a protein that when added to skincare is very useful for moisturising the skin. In the hydrolysed form, the peptides are thought to be able to tell the skin to make more collagen – though the evidence for this isn’t quite there yet. It is, however, a great moisturiser that has been shown to reduce the effects of skin-ageing such as dryness and wrinkling, predominantly by increasing water content in the stratum corneum.

Hydroquinone

This is usually a prescription only medication that is very effective at treating melasma, pigmentation irregularity due to inflammation or photodamage. The classic formulation with most evidence is 4% Hydroquinone but other concentrations are used. Like many of the prescription only medicines, this is more than just an “appearance “ of change: the treatment is actually working at the cellular level to reduce the production of pigment, so the effects take several weeks to realize. As the old skin exfoliates, the amount of pigment will be less, leading to a more even skin tone.

Hyaluronic Acid

This is a molecule that is found naturally in the skin. HA is amazing at bonding with water and
therefore plumping and repairing the skin barrier
giving the skin a very hydrated look. As it plumps
the skin cells it means that any appearance of
wrinkles is reduce. It’s a huge molecule so it is
not being absorbed into the deeper layers of the
skin to do its job but rather when applied
topically sits on the surface to plump the outer
layer.

Shea Butter

This is a plant fat and is rich in antioxidants and
fatty acids. It contained essential fatty acids
(Vitamin F) as well as Vitamin E, D and A. It is a
fantastic hydrator of the skin and reduces
transepidermal water loss. Fantastic for dry skin
conditions and for windy dry season changes.

Squalene

This is another emollient that has anti-inflammatory properties and supports the skin barrier. Squalene is a lipid that is naturally secreted by the sebaceous gland and is the molecule that stops our skin from drying out. It is predominantly plant sourced and is used to help soften the skin and support the skin when active ingredients are being introduced.

Tretinoin

Tretinoin (retinoic acid) is the retinoid that has the best evidence behind it. This is the retinoid that is approved by the FDA for treatment of photodamage and acne. If your SkinSize dictates you could benefit from a retinoid then it is important to use one that will work. Retinol is a common cosmeceutical found on off-the shelf products that skincare companies know will be easier to use – but that is at the expense of effectiveness. Tretinoin is at least 20 times, and anything up to 100 times more powerful than retinol.

Tretinoin will change how a cell functions, it speeds up the turnover of older cells and encourages newer skin cells to divide more rapidly and build up the layers of the epidermis, thickening it through cell proliferation at the top level. It also increases the production of hyaluronic acid to keep the skin more plump. It can stimulate collagen production and importantly inhibit the breakdown of collagen. Tretinoin is also important to reduce inflammatory pathways in the skin that can contribute to acne and rosacea.

Klira Specials are formulated with a unique goal in mind: to allow everyone to get the benefit of the most effective and well-evidenced active ingredients for their skin.

A higher standard of skincare

Our Medical Team

Founded by, used by and prescribed by leading Dermatologists. The Klira dermatology team are by your side, from the first skin analysis and selection of optimum ingredients for your Klira Special, to supporting you with your broader skin routine.

The lab

Each Klira Special is freshly blended for you each month in our London Lab by our team of world class specialist pharmacists, using cutting edge technology, years of research and data-led science.

GREAT SKIN DOESN’T JUST HAPPEN, IT’S PRESCRIBED